OECD Quantitative Method for Evaluating Efficacy of Liquid Antimicrobials against Candida auris on Hard, Non-Porous Surfaces

Purpose of Test

The OECD Quantitative Method for Evaluating Efficacy of Liquid Antimicrobials against Candida auris on Hard, Non-Porous Surfaces is a carrier-based test method designed to evaluate chemicals for effectiveness against Candida auris. The method has been implemented as an interim guidance document that follows a U.S. EPA BEAD SOP and is recognized by the U.S. EPA.

Summary of Test

In this method, a series of stainless steel disks are inoculated with test organism. The carriers are desiccated and subsequently treated with a sample of the disinfectant. After exposure, the carriers are neutralized and quantitatively assayed for surviving test organism. The resulting plates are incubated, the number of survivors is enumerated and a Log10 reduction is determined as compared to the population control. In order to successfully demonstrate disinfection efficacy, the product must demonstrate a 5 Log10 reduction of Candida auris.